During 2004 and up until the present day, the Government of the United States has continued to prohibit the European laboratory Intervet Holland from selling Cuba vaccines designed to prevent avian diseases, stating that at least 10 per cent of the antigens they contain are produced in the United States. This prohibition includes Marek's vaccine, specifically designed for a type of avian disease, and a quadruple vaccine against other diseases such as Gumboro, Newcastle, bronchitis and reovirus.