The Second Review Conference added, consequently, toxins (both proteinaceous and non-proteinaceous) of a microbial, animal or vegetable nature and their synthetically produced analogues are covered.

Recent research has provided the ability to coat proteinaceous molecules so that they can pass through the stomach unaffected and bind to the mucosal lining of the intestines, where they can enter the blood stream.

(b) Activities: Declaration of sites or facilities, fixed or mobile, with activities that encompass possession, storage, destruction and work with agents; any activity involving genetic modification of an agent or transfer of genetic elements from an agent; any activities involving the breeding of vectors of human, animal or plant diseases, or pests; activities involving micro-encapsulation of live micro-organisms or proteinaceous substances; biodefence activities; and any activities involving vaccination of humans against botulism, smallpox or anthrax.